Throughout the universe of advanced skin care ranges, we hear about all of their exciting ingredients.  From AHA’s and retinols to new peptides, vitamins and antioxidants, these all promise more youthful skin many supported by clinical studies.  Here’s something to think about:

  • At age 30, the loss of oxygen levels in the skin drops by 25%
  • At age 40, the loss of oxygen levels in the skin drops by up to 50%

In highly polluted environments the oxygen loss to the skin can be even higher.


Oxygen.  Nature’s ignition for cellular metabolism is needed for optimum cellular turnover to preserve a youthful skin.  But as we age, our skin’s ability to capture oxygen from blood circulation diminishes.  Capillaries begin to deteriorate limiting circulation of oxygen-loaded hemoglobin and vital skin nutrients.  Moreover, sluggish circulation interferes with the evacuation of toxins leading to skin aging symptoms including wrinkles, age spots and loss of tone and moisture.

Our skin’s thirst for oxygen is vital in the production of collagen.  Essentially, oxygen promotes metabolic processes within the dermis and viable cells to produce a higher state of activity. Oxygen enhances collagen formation in fibroblasts among many other actions resulting in the strengthening of the connective tissue matrix and firm, more youthful looking skin.

Spa Technologies has been working for two decades in formulating advanced skin care that blends liquid oxygen with natural anti-aging peptides, antioxidants, enzymes and more.  Thanks to a scientific breakthrough in liquid oxygen transport called Perfluorodecalin and perfluorohexane also known as PFC’s.

PFC’s are molecules approved by the FDA in the US for use in cosmetic products able to store gases such as oxygen and carbon dioxide. In other words, this molecule acts as a replica of hemoglobin for cellular breathing responsible for flooding oxygen into the connective tissue while extracting (or washing away) carbon dioxide. As such this unique substance may be described as a cosmeceutical, in that its function can be classified as being between a cosmetic and a pharmaceutical.

PFC’s are both hydrophobic and lipophobic so they don’t dissolve in either water or oil.  Since Perfluorodecalin and perfluorohexane are inert, they do not create damaging free radicals.  You can best see this demonstrated in Spa Tech’s signature Oxygen Renewal Complex—a triphased serum.  The product is divided into an orange oil-soluble layer of 5 antioxidants on top, a hydro-soluble middle layer (yellow) with seaweed actives, peptides and hyaluronic acid in the middle, and a clear layer on the bottom with pure liquid oxygen.


Spa Technologies have nine products formulated with liquid oxygen including:

Rosacea Serum, Skin Brightening Booster, Skin Firming Booster, Astaxanthin O2 Calming Gel, Omegaceuticals Calming Serum and Age Defense for Luminous Eyes.  For more information, consult our product profiles on our website

Secondary mechanisms of action include vasoconstriction, angiogenesis, fibroblast proliferation, leukocyte oxidative killing, toxin inhibition and antibiotic synergy. Hyperoxia in normal tissues causes vasoconstriction which reduces post-traumatic tissue oedema, contributing to the treatment of crush injuries, compartment syndromes and burns. This vasoconstriction, however, does not cause hypoxia as this is more than compensated by increased plasma oxygen content and microvascular blood flow.

Oxygen is vital for hydroxylation of lysine and proline residues during collagen synthesis and for cross linking and maturation of collagen which is required for strong wound healing. Lack of oxygen is corrected during HBOT, leading to adequate amounts of mature collagen formation.